FDA lifts hold on one of two Phase 3 gene editing studies by Intellia
Lei Lei Wu / endpoints - The FDA has allowed Intellia Therapeutics to resume one of its two pivotal trials of a gene editing therapy for transthyretin amyloidosis, which is a disease caused by misfolded proteins. Intellia
AI Summary: U.S. regulators have just cleared Intellia Therapeutics’ Phase 3 study of a gene‐editing therapy intended to treat a genetic nerve disorder, effectively rescinding a clinical hold. This development opens the door to renewed patient enrolment and further evaluation of the treatment’s safety and effectiveness.
31,000 Kaiser Permanente workers strike in California, Hawaii
Emily Olsen / healthcaredive - Kaiser workers are calling for increased staffing and wages, which the union argues haven’t kept pace with rising costs. The health system said a generous offer is already on the table.
AI Summary: Reports indicate that roughly 31,000 Kaiser Permanente employees in California and Hawaii staged a coordinated walkout over stagnant wages and challenging working conditions, spotlighting deep-seated labor issues in the healthcare industry.
CMS official defends flat Medicare Advantage rate proposal for 2027
Rebecca Pifer Parduhn / healthcaredive - Medicare director Chris Klomp said the Trump administration is “massively” in support of MA as health insurers cry foul over the meager rate update.
AI Summary: A CMS official defended the administration’s plan to freeze Medicare Advantage rate adjustments for 2027 despite industry outcry. Critics argue the flat-rate approach may hurt patient benefits while officials insist it brings consistency amid a contentious policy environment.
It's freezing cold and you've lost power. Here's what emergency doctors want you to do
medicalxpress - Freezing temperatures and long-term power outages can quickly create dangerous health situations.
AI Summary: Amid relentless subzero temperatures and extended power outages, emergency doctors warn that hypothermia and other dangerous cold‐related complications aren’t a winter novelty. They urge everyone to implement immediate safety measures—yes, even if it means canceling your “adventure.” Follow these guidelines to stay safe until temperatures warm up.
CMS proposes nearly flat Medicare Advantage payments for 2027: 5 notes
Jakob Emerson / beckershospitalreview - CMS proposed its 2027 Medicare Advantage and Part D capitation rates and payment policies Jan. 26, putting forth a slowdown in payment growth after a $25 billion boost for 2026. Five things to know:The post CMS proposes nearly flat Medicare Advantage paym…
AI Summary: The Centers for Medicare & Medicaid Services has unveiled proposals for the 2027 payment rules, featuring nearly flat Medicare Advantage rates and a plan to exclude chart reviews from risk adjustment. This comprehensive policy update may notably impact insurer revenue structures and patient care delivery nationwide.
US life expectancy hit an all-time high in 2024, CDC says
medicalxpress - U.S. life expectancy rose to 79 years in 2024—the highest mark in American history.
AI Summary: Recent CDC data reveal that U.S. life expectancy reached 79 years in 2024—the highest level in American history. Despite the many challenges the nation continues to face, experts point to improvements in healthcare delivery and preventive measures driving this historic milestone.
UnitedHealth CEO Hemsley says insurer will rebate ACA profits to consumers
fiercehealthcare - UnitedHealth Group CEO Stephen Hemsley said that the insurance giant will rebate profits from its Affordable Care Act plans back to customers.
AI Summary: Two stories reveal that UnitedHealth’s CEO announced plans to return profits from its Affordable Care Act plans back to customers, a move designed to ease health‐insurance costs and signal a strategic shift in the company’s approach ahead of congressional testimony.
Oregon baby is still battling infant botulism after ByHeart formula exposure
go - A Portland, Oregon, baby got sick with infant botulism after drinking contaminated ByHeart formula donated through a program that helps poor and homeless families
AI Summary: Two reports describe how a Portland baby continues to struggle with severe infant botulism after ingesting contaminated ByHeart formula distributed via a charity, raising concerns about quality control and the safety of aid programs.
Colorectal Cancer Is Now the Leading Cause of Cancer Death Under 50 – Fight Colorectal Cancer
oncodaily - Fight Colorectal Cancer shared a post on LinkedIn: “Breaking news: Colorectal cancer is now the leading cause of cancer death for people under 50, according to new data released by […]
AI Summary: Recent research indicates a stark shift in cancer mortality as colorectal cancer now leads as the top killer among Americans under 50. Studies highlight an earlier disease onset with increasing incidence, prompting urgent calls for revised screening guidelines and robust public health interventions to address this alarming trend.
US officially leaves World Health Organization
bbc - Trump ordered the withdrawal a year ago, accusing the UN agency of failing to adopt reforms and mishandling the pandemic.
AI Summary: The U.S. has officially completed its exit from the World Health Organization—a policy ordered over a year ago—while uncertainties remain regarding the full finalization timeline. This move marks a dramatic reorientation of America’s role in global health governance.
‘Vertical integration is destroying people’s ability to access care’: Payer CEOs face bipartisan congressional grilling
Jakob Emerson / beckershospitalreview - The CEOs of the nation’s largest health insurers drew the ire of lawmakers on both sides of the aisle during congressional hearings Jan. 22 over industry consolidation, prior authorization practices and executive pay, with members pressing executives to e…
AI Summary: Lawmakers grilled top health insurance executives in a high‐profile congressional hearing over rising healthcare costs, vertical integration and shifting of cost burdens to hospitals and drug makers. The grilling highlighted deep concerns over patient access and systemic inefficiencies in American healthcare.
5,500-year-old human skeleton discovered in Colombia holds the oldest evidence yet that syphilis came from the Americas
livescience - An ancient DNA analysis of a 5,500-year-old human skeleton reveals that an ancestor of the bacterium that causes syphilis was present in the Americas at least 3,000 years earlier than previously thought.
AI Summary: Researchers have uncovered compelling genetic evidence in 5500‐year‐old human remains from Colombia that extend the timeline for the syphilis-causing bacterium by thousands of years. The findings challenge long-held views on the disease’s emergence and suggest a broader, earlier evolutionary history in the Americas.
Why doing a mix of exercise could be the key to longer life
bbc - Don't just focus on one activity - doing a variety every week gives you more health benefits, a study suggests.
AI Summary: Recent research highlights that combining different types of physical activity – rather than sticking with just one – is associated with longer life and improved health. Experts suggest that cross-training may offer cumulative benefits that help maintain overall fitness and reduce risks linked to a sedentary lifestyle.
Epic & Providers Sue Health Gorilla Over Alleged Data Exploitation
Katie Adams / medcitynews - Epic Systems and several healthcare providers have sued Health Gorilla and other companies, alleging they exploited interoperability networks to improperly access and monetize nearly 300,000 patient medical records without consent.The post Epic & Provider…
AI Summary: A lawsuit has been filed by Epic Systems along with several major healthcare providers alleging that Health Gorilla exploited interoperability networks to access patient records for financial gain. The legal action raises questions about data security practices in digital health exchanges.
US overdose deaths fell through most of 2025, federal data reveals
go - U.S. overdose deaths fell through the most of last year, suggesting a lasting improvement in an epidemic that had been worsening for decades
AI Summary: New federal data reveal that overdose fatalities in the United States dropped markedly throughout most of 2025, signaling a potential turning point in a decades‐long worsening epidemic. Concerns over opioid misuse remain, but these trends hint at improved outcomes.
European women's lung cancer mortality rates predicted to level off by 2026
medicalxpress - After increasing for more than 25 years, lung cancer death rates are finally leveling off among women in European Union (EU) countries apart from Spain, according to predictions of mortality rates from the disease for 2026.
AI Summary: After more than 25 years of steadily rising death rates, recent findings indicate that lung cancer mortality among European women is now stabilizing—with projections extending to 2026 in most EU nations. Health experts view this as a promising sign that improved screening, prevention, and treatment strategies are beginning to have an impact.
F.D.A. Decisions on Abortion Pill Were Based on Science, New Analysis Finds
Pam Belluck / nytimes - A study of more than 5,000 pages of agency documents on mifepristone over 12 years found that agency leaders almost always followed the evidence-based recommendations of scientists.
AI Summary: New in‑depth analyses of internal FDA documents reveal that regulatory decisions on the abortion pill mifepristone were firmly based on thorough evidence rather than political pressure, dispelling common misconceptions about politicized review processes.
No Link Between Acetaminophen in Pregnancy and Autism, a New Study Finds
Azeen Ghorayshi / nytimes - The review looked at more than three dozen studies and found no evidence that acetaminophen increased the risk of neurodevelopmental disorders in children.
AI Summary: A new comprehensive review of more than three dozen studies found no evidence that taking acetaminophen during pregnancy increases the risk of neurodevelopmental disorders such as autism, ADHD or intellectual disabilities. Despite lingering public anxiety and the occasional skeptical quip, expectant mothers can take a breath of relief.
Life-extending prostate cancer drug to be offered to thousands in England
bbc - Abiraterone will be available in a matter of weeks and will be offered to 7,000 men a year.
AI Summary: Health authorities in England have announced that nearly 7,000 additional men with hormone‐sensitive prostate cancer will soon be eligible for abiraterone—a breakthrough treatment that extends survival. The drug is expected to be available within weeks, marking a significant step forward in targeted prostate cancer care.
FDA rejects cancer therapy for rare post-transplant disease
Ella Jeffries / beckershospitalreview - Atara Biotherapeutics received a second complete response letter from the FDA for its biologics license application for Ebvallo (tabelecleucel). The letter, received Jan. 9, said the FDA no longer considers the single-arm ALLELE trial adequate to support …
AI Summary: The FDA has again rejected Atara’s cell therapy aimed at treating rare post‐transplant complications linked to Epstein–Barr virus. Despite high hopes for this innovative approach, regulatory concerns remain over its safety and efficacy—clearly a “repeat performance” in the world of breakthrough therapies.