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StackHealth / Rogaratinib shows activity in SDH‑deficient GIST phase 2 trial

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AI Summary: A phase 2 study investigated FGFR inhibition with rogaratinib in succinate dehydrogenase–deficient gastrointestinal stromal tumors. Results reported tumor control in this rare molecular subset, offering a targeted therapeutic approach where options are sparse and validating FGFR as a biologic vulnerability in SDH‑deficient GIST.

#pharmaceuticals #biotech #drugdevelopment #oncology #cancerresearch #clinicaltrials #genetics

37 hrs / oncodaily

40 hrs / oncodaily

3 days / kffhealthnews


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