Congo says its mpox outbreak is over after 2 years and more than 2,200 suspected deaths

abcnews - Congo has declared the end of a two-year mpox outbreak, which is believed to have caused over 2,200 deaths

AI Summary: Republic of the Congo announced its prolonged mpox outbreak has ended after roughly two years and more than 2,200 suspected deaths, even as genomic surveillance uncovered co-circulating clades, including evidence of clade IIb lineage A.2.2. Health officials now face the twin tasks of documenting lessons and monitoring for lingering transmission.

What you should know about the new COVID-19 'Cicada' variant

medicalxpress - A new COVID-19 variant that some have dubbed the "Cicada" variant is quietly spreading across the globe, carrying an unusually high number of mutations that could help it slip past existing immunity, public health experts say. The strain of SARS-CoV-2, ca…

AI Summary: A newly identified SARS‑CoV‑2 lineage nicknamed "Cicada" is showing signs of increased spread, prompting CDC tracking and expert concern. Public health officials advise heightened surveillance, updated testing and genomic sequencing to determine transmissibility, immune escape and clinical impact, while researchers rush to characterize the variant’s risks and inform any needed response.

Global study estimates over 250,000 meningitis deaths in 2023, with young children bearing a heavy toll

medicalxpress - In 2023, 259,000 people died from meningitis and 2.5 million people were infected with the disease globally, suggests a study published in The Lancet Neurology. Although death and infection rates have declined significantly since 1990, progress is insuffi…

AI Summary: A worldwide mortality analysis estimates more than 250,000 deaths from meningitis in 2023, with young children bearing the heaviest toll. The findings underline gaps in vaccination, surveillance and outbreak preparedness, and call for accelerated prevention efforts—particularly on campuses and in high‑risk populations—before the predictable heartbreak rolls around again.

Do you love sleeping with your pet? Science reveals there's a tricky trade‑off

medicalxpress - For some pet guardians, their pets are present in their lives from the moment they wake up to the moment they go to bed. This happens because cats, dogs and other companion animals are increasingly perceived as family members. I'm not talking about the di…

AI Summary: New research finds sleeping with pets can boost comfort and emotional wellbeing, but carries trade-offs: increased allergen exposure, more fragmented sleep and small infection risks. Experts advise weighing mental‑health gains against sleep quality and hygiene, and using pet‑free bedrooms when needed — because 'cute' is not a medical recommendation.

Pfizer Lyme vaccine candidate heads to FDA

Ella Jeffries / beckershospitalreview - Pfizer and Valneva’s investigational Lyme disease vaccine candidate, PF-07307405 (LB6V), demonstrated more than 70% efficacy in preventing Lyme disease among individuals age 5 and older, according to topline phase 3 trial results. The prespecified analysi…

AI Summary: Pfizer is advancing a Lyme disease vaccine toward FDA submission despite a messy late‑stage picture: efficacy signals above 70% were reported while a pivotal trial missed its primary endpoint and struggled with low case numbers. Regulators must weigh public health need against statistical nuance as the company pushes for licensure.

This common vaccine cuts heart risk nearly in half in new study

sciencedaily - A shingles vaccine might double as a powerful heart protector. In people already at high risk, it cut major cardiac events by 46% and deaths by an impressive 66% within a year. Scientists think preventing shingles may also stop clot-related complications …

AI Summary: New research finds that receipt of a common shingles vaccine is associated with roughly a 50% reduction in serious cardiac events in the studied population. Investigators propose immune‑modulating mechanisms may underlie the protective effect; if confirmed, the vaccine could offer a tidy twofer—preventing shingles and cutting heart risk—proof that prevention sometimes moonlights as cardiology.

A liquid biopsy blood test may improve children's survival of cancer in Africa

medicalxpress - In a study published in Nature Medicine, researchers from the University of Oxford and the Muhimbili University of Health and Allied Sciences (MUHAS) in Dar es Salaam, Tanzania have shown that a minimally invasive liquid biopsy test can diagnose Burkitt l…

AI Summary: A blood‑based liquid biopsy for EBV‑positive Burkitt’s lymphoma shows promise for earlier, less invasive diagnosis in endemic regions, potentially improving pediatric survival where tissue biopsies are scarce. Early data indicate actionable sensitivity and feasibility for low‑resource settings, offering a scalable path to faster treatment.

F.D.A. Investigates 7 E. Coli Illnesses as Raw Dairy Farm Denies Any Link

Christine Hauser and Alice Callahan / nytimes - The outbreak has sickened people in California, Texas and Florida. The agency said Cheddar cheese products from Raw Farm are “the likely source,” but the company denies it and has not recalled them.

AI Summary: Federal investigators are probing seven E. coli infections across multiple states tied to cheddar cheese produced from raw milk. The implicated Raw Farm cheddar is the suspected source; the producer denies responsibility as public health officials trace exposures and warn consumers while urging caution around unpasteurized dairy.

Trial finds vitamin D supplements don't reduce COVID severity but could reduce long COVID risk

medicalxpress - In a large, randomized trial, researchers at Mass General Brigham found that high-dose vitamin D3 did not reduce COVID-19 infection severity, but may impact long COVID outcomes. Results of the study are published in The Journal of Nutrition.

AI Summary: A large randomized trial found high‑dose vitamin D3 did not lower acute COVID‑19 severity but revealed a surprising signal: supplementation may reduce the risk of developing long‑COVID. The result complicates the vitamin D narrative — not a cure, perhaps a modest shield against persistent post‑infectious symptoms worthy of further investigation.

Measles outbreaks could fuel rise in fatal complication, physicians warn

Mackenzie Bean / beckershospitalreview - As measles continues spreading across the U.S. at a pace not seen in decades, physicians are warning about a rare but often fatal neurological complication that can emerge years after initial infection, KFF Health News reported March 13. Subacute sclerosi…

AI Summary: Measles is resurging across the United States at levels not seen in decades, and clinicians warn this spike could drive an increase in a rare but often fatal neurological complication. Public‑health experts point to falling vaccination coverage and gaps in outbreak control as the drivers, urging renewed immunization efforts and vigilance.

Flu vaccines didn't work that well in the US, officials find

medicalxpress - As the U.S. flu season winds down, health officials say the flu vaccine didn't work very well, with one of its worst effectiveness rates in more than a decade.

AI Summary: Health officials report this season’s influenza vaccine performed poorly, with effectiveness among the lowest in recent years. A mismatch between vaccine strains and circulating viruses reduced protection, prompting calls for strain updates ahead of the fall program. Public health leaders still urge vaccination for partial protection and to blunt severe outcomes.

Severe COVID or Severe Flu May Raise Risk of Lung Cancer, But Vaccines Helped in Animal Tests

discovermagazine - Learn how severe respiratory illness leaves the lungs vulnerable to cancer, and how vaccines could prevent these vulnerabilities.

AI Summary: New animal and observational evidence suggests severe respiratory infections—including serious COVID‑19 and influenza—can prime lung tissue and accelerate cancer development months to years later. Vaccination appeared to blunt those effects in experimental models, highlighting prevention as a potential cancer‑risk reduction strategy and urging clinicians to watch survivors of severe infections more closely.

CART19-BE-02 trial: From Bench to Bedside and Beyond – Resonance

oncodaily - ALRCaN presents “CART19-BE-02 trial: From Bench to Bedside and Beyond—Implementing a Hospital-Based CAR T Program and Integrating It into the Spanish NHS” with Dr. Valentín Ortiz-Maldonado. “Dear friends and colleagues, […]

AI Summary: Bereaved relatives delivered searing final testimonies as the Covid inquiry wound up four years of public hearings, recounting loved ones who died alone and demanding answers. Chair Baroness Heather Hallett defended the process and its roughly £200 million price tag as necessary to finish the work, despite public frustration and political scrutiny.

Moderna to Pay Up to $2.25B to Settle Patent Suit Over Covid-19 Vaccine Technology

Frank Vinluan / medcitynews - Under the settlement, Genevant Sciences and Arbutus Biopharma will grant Moderna a non-exclusive license to their lipid nanoparticle technology for mRNA delivery in infectious disease vaccines. If Moderna’s full financial payout to the companies is reache…

AI Summary: Moderna has agreed to settle long-running patent disputes over its COVID-19 vaccine technology for up to $2.25 billion, resolving litigation with several claimants. The deal provides Moderna with broad licensing rights and clears a major legal uncertainty, allowing the company to move forward without another courtroom cliffhanger.

FDA vaccine chief to step down in April

Ella Jeffries / beckershospitalreview - Vinay Prasad, MD, the FDA’s top regulator of vaccines and cell and gene therapies, will step down at the end of April, an agency spokesperson confirmed to Becker’s. Dr. Prasad joined the agency in 2025 on a one-year sabbatical from the University of Calif…

AI Summary: Vinay Prasad, the FDA’s top regulator for vaccines and cell and gene therapies, will step down at the end of April amid mounting criticism over controversial decisions that reportedly overrode agency scientists and spooked stakeholders. His exit follows prolonged internal and external disputes about regulatory judgment and leadership style.

RFK Jr. names 2 new members to CDC vaccine panel

Erica Cerutti / beckershospitalreview - HHS Secretary Robert F. Kennedy Jr. appointed two new members to the CDC’s vaccine advisory committee Feb. 27, ahead of a rescheduled meeting in mid-March where members are expected to review COVID-19 vaccine recommendations. Mr. Kennedy said Sean Downing…

AI Summary: HHS Secretary Robert F. Kennedy Jr. appointed two clinicians to the CDC’s Advisory Committee on Immunization Practices just weeks before a rescheduled session, installing new voting members ahead of vaccine deliberations. The last‑minute nominations aim to ensure the panel is fully staffed for upcoming guidance discussions.