Supercentenarians have an abundance of cancer-killing immune cells
medicalxpress - The human immune system has specialized cells called CD4 cytotoxic T lymphocytes (CD4 CTLs), which have been shown to kill tumor cells in some cancers. When a person gets sick, these cells multiply in a process called clonal expansion to help fight infect…
AI Summary: Analyses of people over 110 reveal an abundance of highly active cytotoxic immune cells capable of recognizing and eliminating cancerous cells, offering clues to extreme longevity. These hypervigilant immune profiles may explain low cancer rates among the very old and suggest immune‑based strategies that could one day mimic their natural defenses.
Ultragenyx Gene Therapy Becomes First FDA-Approved Treatment for Ultra-Rare Disease
Frank Vinluan / medcitynews - Ultragenyx Pharmaceutical’s Genglycos received accelerated FDA approval for glycogen storage disease type Ia, an inherited enzyme deficiency. It’s also the first approved gene therapy for Ultragenyx, which specializes in rare disease treatments. The post …
AI Summary: Ultragenyx received FDA approval for a gene therapy, marking the first approved treatment for that particular ultra‑rare disorder. The decision provides a regulated therapeutic option for patients previously without approved care, highlighting the evolving regulatory willingness to greenlight transformative but small‑population medicines.