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for: Wednesday, August 19, 2026



Merck and Moderna’s Intismeran Autogene Plus Keytruda Meets Phase 3 RFS and DMFS Endpoints in Resected Melanoma

oncodaily - Merck and Moderna announced positive topline results from the Phase 3 INTerpath-001 trial, evaluating intismeran autogene (V940/mRNA-4157) plus Keytruda (pembrolizumab) as adjuvant treatment for patients with completely resected stage IIB-IV […]

AI Summary: Merck and Moderna announced that their mRNA-based melanoma vaccine, given with Keytruda, met key phase‑3 endpoints — reducing recurrence and distant metastasis after resection. The data suggest the vaccine can prime anti‑tumor immunity to prevent relapse, positioning it as a potential adjunct to standard checkpoint inhibition in high‑risk patients.


Experts weigh in on personalized mRNA cancer vaccines

Paolo A. Ascierto: Positive Phase 3 KEYTRUDA Results Advance Personalized Melanoma Treatment

8 days / oncodaily

Marco Donia: First Positive Phase 3 Trial of a Personalized Neoantigen Therapy in Cancer

8 days / oncodaily

INTerpath-001 Trial: Personalized mRNA Cancer Vaccine for Melanoma

9 days / oncodaily

Will personalised mRNA vaccines transform cancer treatments?

9 days / newscientist / Michael Le Page


INTerpath-001: phase‑3 vaccine reduces melanoma recurrence

Moderna and Merck Announce Positive Phase 3 INTerpath-001 Results in Melanoma

9 days / oncodaily

Vaccine breakthrough stops cancer returning in trial

10 days / bbc

Merck, Moderna Personalized mRNA Cancer Therapy Achieves a First for Melanoma

10 days / medcitynews / Frank Vinluan

Moderna, Merck Say mRNA Vaccine Prevents Melanoma From Returning

10 days / nytimes / Carolyn Y. Johnson

Merck, Moderna claim 'promising' skin cancer vaccine results in key trial

10 days / medicalxpress

Merck and Moderna’s Intismeran Autogene Plus Keytruda Meets Phase 3 RFS and DMFS Endpoints in Resected Melanoma

11 days / oncodaily


Market surge: Moderna's stock jumps after trial news

Moderna’s Shift to Cancer Company Lifts Stock Up 177%

9 days / nytimes / Rebecca Robbins

Noubar Afeyan: Moderna and Merck Announce Positive Phase 3 Results in Melanoma

10 days / oncodaily

Moderna shares surge after it says its experimental mRNA cancer treatment passed a key test

10 days / abcnews


All Other Stories

Rob Davis: Individualized Neoantigen Therapy Transforms Adjuvant Melanoma Care

9 days / oncodaily



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