Early-onset cancers are on the rise: Knowing family history is crucial

medicalxpress - In the U.S., more than a dozen kinds of cancer are on the rise in adults under 50. Among these early-onset cancers, colorectal and breast cancers have increased the most, and colorectal cancer is now the deadliest cancer for Americans ages 18 to 49.

AI Summary: New analyses show early‑onset cancers are increasing and reinforce that detailed family history remains a key tool for risk assessment and targeted screening. Experts urged clinicians and health systems to prioritize family‑history collection and cascade testing to catch at‑risk individuals sooner and reduce preventable morbidity.

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• Colorectal cancer: rising cases and screening gaps worldwide (6)
• Faster biological aging linked to early-onset cancer rise (5)
• Inherited cancer risk and genomics driving early diagnoses (6)
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Breast cancer risk: AI tools, polygenic scores, prevention

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