Monday, March 09, 2026

In Detail Full day, Monday, March 09, 2026, Timezone: America/Chicago

Effects of daily multivitamin–multimineral and cocoa extract supplementation on epigenetic aging clocks in the COSMOS randomized clinical trial

Sidong Li / nature - Nature Medicine, Published online: 09 March 2026; doi:10.1038/s41591-026-04239-3In a prespecified ancillary analysis of the COSMOS randomized trial, supplementation with daily multivitamins, but not with cocoa extract, over the course of 2 years decreased…

AI Summary: A prespecified ancillary analysis of the COSMOS randomized trial found that daily multivitamin–multimineral (with cocoa extract) modestly slowed epigenetic aging clocks over two years. The Nature Medicine report highlights measurable shifts in biomarkers of biological aging, while noting uncertain clinical significance and the need for longer follow-up.

Engineering CAR T cells to secrete VEGF-neutralizing scFvs enhances antitumor activity against solid tumors

Torahito A. Gao, Ryan M. Shih, Justin D. Clubb, Shao-Hsi Hung, Tanya Singh, Laura B. James-Allan, Ga / science - Science Translational Medicine, Volume 18, Issue 839, March 2026.

AI Summary: Researchers engineered CAR‑T cells to secrete VEGF‑neutralizing single‑chain antibodies, improving infiltration and antitumor activity against solid tumors in preclinical models. By locally neutralizing VEGF, the approach remodels the tumor microenvironment and enhances CAR‑T efficacy, offering a plausible strategy to overcome the long‑standing barrier of poor CAR‑T performance in solid cancers.

White House autism briefing linked to swift shifts in prescribing patterns

medicalxpress - A White House briefing in September 2025 that raised concerns about acetaminophen use during pregnancy and promoted the drug leucovorin as a potential autism treatment was followed by sharp changes in how doctors prescribed those medications nationwide, a…

AI Summary: A White House briefing warning about acetaminophen in pregnancy and promoting alternate therapies led to an immediate, measurable decline in ER acetaminophen orders for pregnant patients. The episode shows how high‑profile public messaging can swiftly reshape clinical behavior — for better or worse — and raises questions about evidence, communication and unintended consequences.

MUSC Health acquires South Carolina's largest multispecialty practice for $111M

fiercehealthcare - The deal, effective March 3, includes 126 physicians and advanced practitioners, expanding the academic system's primary care capacity.

AI Summary: MUSC Health completed a $111 million acquisition of a major South Carolina multispecialty practice, expanding its primary care and outpatient capacity. The deal consolidates regional services under the academic system’s umbrella, promising integrated care and scale efficiencies — and yes, another hospital system just got a bit larger.