Swallowing faecal capsules reduces peanut allergy in six adults
Alice Klein / newscientist - Altering the gut microbiomes of people with peanut allergy using faeces donated from an allergy-free individual improved their peanut tolerance in a clinical trial
AI Summary: A small human trial showed swallowing fecal microbiota capsules reduced peanut allergy responses in six adults, while parallel animal and mechanistic work implicates bile-acid metabolites in restoring oral tolerance. The findings revive interest in microbiome-based desensitization, though larger trials are required before anyone starts prescribing ‘poop pills’ as routine therapy.
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