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AI Summary: Divarasib delivered superior responses to existing KRAS G12C inhibitors in a head‑to‑head trial for KRAS G12C‑mutant non‑small‑cell lung cancer, producing higher tumor response and longer disease control while maintaining a manageable safety profile. The data position divarasib as a serious contender to displace older G12C agents if the effect holds up.
FDA speeds approval for dostarlimab in MSI‑H rectal cancer / 36 hrs
FDA clears first targeted therapy for ultra-rare NRG1-driven cholangiocarcinoma / 5 months
CA017‑078 results prompt reevaluation of perioperative nivolumab in MIBC / 24 hrs
Individualized mRNA neoantigen vaccine shows phase III success in melanoma / 27 hrs
Trastuzumab rezetecan (HORIZON‑Breast06) slashes progression risk by 73% / 37 hrs
Enhertu (DESTINY‑Lung04) improves PFS in HER2‑mutant lung cancer / 2 months
ENZAMET trial confirms long-term survival benefit of enzalutamide in mHSPC / 2 months
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