FDA Approves Decnupaz (pivekimab sunirine-pvzy), the First ADC for Adults With BPDCN
oncodaily - On May 27, 2026, the U.S. FDA granted approval to pivekimab sunirine-pvzy (Decnupaz, AbbVie, Inc.), a CD123-directed antibody and alkylating agent conjugate, for the treatment of adults with blastic plasmacytoid […]
AI Summary: The FDA approved pivekimab sunirine (Decnupaz/pvzy), the first antibody‑drug conjugate for blastic plasmacytoid dendritic cell neoplasm (BPDCN), marking a regulatory win for an ultra‑rare blood cancer. The decision underscores ADCs’ growing role in niche hematologic malignancies and anchors AbbVie’s expanding ADC strategy.
- ASCO 2026: ADC education, efficacy signals, and ocular toxicity (4)
- Decnupaz approval reshapes BPDCN treatment landscape (4)
- Real-world ADC safety: infection risks and rechallenge questions (3)
ASCO 2026: ADC education, efficacy signals, and ocular toxicity
Decnupaz approval reshapes BPDCN treatment landscape
Real-world ADC safety: infection risks and rechallenge questions
Related Stories
FDA approves Replimune’s Tudriqev after repeated rejections / 22 days
FDA to revisit Atara/Pierre Fabre cell therapy approval for rare lymphoma / 3 months
FDA advisory panel rejects camizestrant after SERENA‑6 results / 3 months
Bristol Myers Squibb wins first-in-class approval for protein‑degrader myeloma therapy / 15 days
Belzutifan plus pembrolizumab gains approval for adjuvant RCC / 5 wks
FDA greenlights datopotamab deruxtecan for metastatic TNBC / 2 months
FDA approves belzutifan (Welireg) plus pembrolizumab for adjuvant RCC / 2 months
StackHealth RSS
You can now follow topics by RSS - browse the complete list of topics, people, and organizations. Or, try Pediatric Oncology, Venture Capital, Avian Influenza, Telemedicine and look for the RSS link.
StackHealth Time Machine